ANALYSIS OF THE PERIOPERATIVE STATE OF PATIENTS WITH SURGICAL AORTIC PATHOLOGY BASED ON A COMPARISON OF THE GENERAL FUNCTIONAL PARAMETERS OF THE ORGANISM
Keywords:
perioperative condition, surgical aortic pathology, meglumine sodium succinate, D-fructose-1,6-diphosphate sodium salt hydrate.Abstract
The question of optimization of anesthetic support in patients with surgical correction of aortic pathology remains open, relevant. The purpose of our work was to analyze the perioperative state of patients with surgical pathology of the aorta based on a comparison of the general functional parameters of the organism. The basis of this study is the analysis of the results of the study in 118 patients with aortic surgery. Patients were divided into 2 groups based on the use of additional substances in the form of intensive care (IC) of additional substances. 46 patients were included in group I, which in addition to the IT algorithm a solution of meglumine sodium succinate (reamberine) was assigned, and 46 patients were included in the II group, which in addition to the IT algorithm was assigned a solution of D-fructose-1,6-diphosphate sodium hydrate salt (ezofosfina). The control group consisted of 26 patients who had surgical pathology of the aorta, according to all criteria, coincided with the patients in groups I and II, but had no additional substance in the IT. The patients’ status was determined on the basis of the EuroSCORE II postoperative mortality scale, the depth of anesthesia with a BIS monitor, the qualitative composition of the leukocyte formula, nasal and rectal temperature, blood composition, electrolyte levels, glucose, lactate, coagulogram, hemolysis and phosphate levels. Except a significant difference in phosphorus levels, we did not discriminate between the groups. It can be argued that supplementation with the intensive therapy in group I of sodium methluminium succinate solution and in the group II solution of D-fructose-1,6-diphosphate sodium hydrate salt do not significantly affect the leading functional parameters of the general condition of patients, but realize their mechanisms of action exclusively in relation to the interaction of the influence of hypoxia and the patient’s macroorganism.
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