TARGETED CEREBRAL PERFUSION IN NEONATAL INTENSIVE CARE
DOI:
https://doi.org/10.31379/2411.2616.18.2.9Keywords:
cerebral perfusion, newborns, intensive care.Abstract
NIRS signal decreasing reflects low oxygen delivery to the brain tissue but can’t answer if it been related to hypoxia or ischemia. Doppler evaluation of cerebral blood flow in anterior cerebral artery in addition to NIRS monitoring should be the method which will distinguish proper ischemia and help neonatologist to decide what to do aiming hemodynamic support and/or oxygen supply. Relations between NIRS, Doppler cerebral blood flow and hemodynamic parameters in six term babies with severe HIE were evaluated. Considering rSO2 more depends on circulatory sufficiency then FiO2 it is expedient to use such a definition as “oxygen price of saturation”. In that case using of Doppler estimation of cerebral blood flow pattern allows differing mixed hypoxia and cerebral ischemia aiming to choose proper ways of intensive care.
References
Cerebral oximetry in children: so NIRS yet so far / James A. DiNardo // Anesth & Analg. – 2019. – Vol. 128(4). – P. 605–606. DOI: 10.1213/ane.0000000000002844
Monitoring cerebral oxygenation in neonates: an update / L.M. Dix, F. van Bel, P.M. Lemmers // Front Pediatr. – 2017. – Vol. 5. – P. 46. DOI: 10.3389/fped.2017.00046
Neonatal cerebrovascular autoregulation / C.R. Rhee, C.S. da Costa, T. Austin [et al.] // Pediatr Res. – 2018. – Vol. 84(5). – P. 602–610. DOI: 10.1038/s41390-018-0141-6
The SafeBoosC phase II clinical trial: an analysis of the interventions related with the oximeter readings / J. Riera, S. Hyttel-Sorensen, M.C. Bravo // Dis Child Fetal Neonatal Ed. – 2016. – Vol. 101(4). – P. F333–8. DOI: 10.1136/archdischild-2015-308829
Cerebral blood volume during neonatal transition in term and preterm infants with and without respiratory support / B. Schwaberger, G. Pichler, C. Binder-Heschl [et al.] // Front. Pediatr. – 2018. – Vol. 6. – P. 132. DOI: 10.3389/fped.2018.00132
